Scientific Archive

Keith D. Garlid, M.D., PhD

Professor Emeritus, Portland State University
Renowned Investigator in Mitochondrial Bioenergetics, Ion Transport, and Cardioprotection

Dr. Keith D. Garlid is an internationally recognized biomedical scientist known for pioneering work on mitochondrial potassium channels (mitoKATP), uncoupling proteins (UCPs), the mitochondrial calcium cycle, and cellular bioenergetics. This site serves as an academic archive of his scientific contributions, trainee records, publications, and scientific collaborations.

Biographical Summary

Academic & Career Milestones

  • Professor Emeritus, Department of Biology, Portland State University.
  • Consulting Professor, Department of Physiology, UCLA (Dr. Peipei Ping Lab, 2016–2020).
  • Professor & Director, Department of Chemistry, Biotechnology, & Medicine, Medical College of Ohio.
  • M.D., PhD Bioenergetics, Johns Hopkins University School of Medicine.

Core Areas of Impact

  • mitoKATP & Cardioprotection: Discovery and functional characterization of mitochondrial KATP channels in heart muscle protection.
  • Uncoupling Proteins (UCPs): Mechanisms of fatty acid-mediated proton transport across mitochondrial inner membranes.
  • Mitochondrial Calcium Cycle: Kinetics of calcium transport and signaling pathways in cellular bioenergetics.
  • Peter Mitchell Collaboration: Decades of scientific discourse and friendship with the 1978 Nobel laureate.

Featured Publications

2018Uncoupling proteins (UCPs) & obesity

Mitochondrial Uncoupling Proteins: Subtle Regulators of Cellular Redox Signaling

Ježek P, Holendová B, Garlid KD, Jabůrek M.

Antioxid Redox Signal. 2018 Sep 1;29(7):667-714. doi: 10.1089/ars.2017.7225. Epub 2018 Mar 14. doi:10.1089/ars.2017.7225

2017Water state in mitochondria, IMAC, & bioenergetics

Equipping Physiologists with an Informatics Tool Chest: Toward an Integrated Mitochondrial Phenome

Garlid AO, Polson JS, Garlid KD, Hermjakob H, Ping P.

Handb Exp Pharmacol. 2017;240:377-401. doi: 10.1007/164_2016_93. doi:10.1007/164_2016_93